Automated assessment of keratocyte density in clinical confocal microscopy of the corneal stroma
نویسندگان
چکیده
منابع مشابه
Automated quantification of keratocyte density by using confocal microscopy in vivo.
PURPOSE To compare keratocyte density determined by using confocal microscopy with keratocyte density determined in the same corneas by histology. METHODS Digital en face images of central corneas were recorded three times by using confocal microscopy in vivo in six New Zealand White rabbits. Bright objects (keratocyte nuclei) in the images were automatically identified by using a custom algo...
متن کاملNormal human keratocyte density and corneal thickness measurement by using confocal microscopy in vivo.
PURPOSE To quantify keratocyte density according to stromal region and subject age and to measure the thickness of the normal human cornea and its layers in vivo. METHODS Seventy normal corneas of 70 subjects were examined by confocal microscopy (contact lens wearers were excluded). Ages of subjects ranged from 12 to 80 years, with 10 subjects per decade. Images were recorded by continuously ...
متن کاملClinical applications of corneal confocal microscopy
Corneal confocal microscopy is a novel clinical technique for the study of corneal cellular structure. It provides images which are comparable to in-vitro histochemical techniques delineating corneal epithelium, Bowman's layer, stroma, Descemet's membrane and the corneal endothelium. Because, corneal confocal microscopy is a non invasive technique for in vivo imaging of the living cornea it has...
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In vivo confocal microscopy (IVCM) has become a widely accepted imaging technique to study the human living cornea. It provides a unique opportunity to visualize the corneal tissue at the cellular level without damage and longitudinally observe its pathologic and normative changes. With rapidly evolving technology, there has been an abundance of interest in maximizing its potential to better un...
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data envelopment analysis (dea) is a powerful tool for measuring relative efficiency of organizational units referred to as decision making units (dmus). in most cases dmus have network structures with internal linking activities. traditional dea models, however, consider dmus as black boxes with no regard to their linking activities and therefore do not provide decision makers with the reasons...
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ژورنال
عنوان ژورنال: Journal of Microscopy
سال: 2008
ISSN: 0022-2720,1365-2818
DOI: 10.1111/j.1365-2818.2007.01870.x